Fibrinolysis in leukaemia

Fibrinolysis in myocardial infarction.

Fibrinolysis is the process of fibrin digestion by an enzyme system present in the blood. Although fibrinolytic activity has been found in the normal, and in many pathological states, its role remains obscure. It seems likely, however, that such a process may take part in the normal hamostatic equilibrium of the body and may be operative in the processes of resolution and healing (Astrup, 1956)...

Fibrinolysis in subarachnoid haemorrhage.

RECURRENT subarrachnoid haemorrhage from intrachanial aneurysms most commonly occurs during the 2nd, 3rd and 4th weeks after the initial ictus, and after 8 weeks the recurrence rate, approaching 50% in untreated cases, falls sharply (Hamby, 1948; Walton, 1952; Holmes, 1957; McKissoch, Paine & Walshe, 1958). For those patients having no surgery who survive 6 weeks after subarachnoid haemorrhage,...

Fibrinolysis in normal pregnancy.

It is well known that a low level of circulating fibrinogen may be associated with bleeding in a variety of obstetric complications, as, for example, accidental haemorrhage. The actual cause, however, ofthe depletion offibrinogen in these conditions is debatable (Moore, 1955), but one feature of such states is the frequent presence of a circulating proteolytic agent which is capable of destroyi...

Glutathione S-transferases Null Genotype in Acute Myeloid Leukaemia

Background: The glutathione S-transferase (GST) family of metabolising enzymes plays an important role in the detoxification of mutagens and carcinogens. The expression of many of these cancer susceptibility enzymes is genetically polymorphic. An increased frequency of GST-null genotypes has been associated with several malignancies. Objective: To investigate the rate of GSTT1 and GSTM1 null ge...

Comparative Fibrinolysis